We are pleased to invite you to our next webinar #3. Two interesting presentations are waiting for you. Our first speaker is Jason Ewanicki from Pfizer whose topic is “2H SOLCOR: A novel tool for reducing volume variation as a source of error in external standard quantitative NMR“. Tube to tube volume difference presents a challenge in obtaining accurate external standard quantitative NMR (esqNMR) results. Deuterium (2H) is easily observable, intrinsically quantitative, present in all samples, free of interfering signals, insensitive to probe tune/match and sample saltiness. These properties make 2H SOLCOR (2H observed SOLvent CORrected) an ideal tool for volume correction whenever difference exist between reference standard and analyte, such as esqNMR. We demonstrate a technique where 2H peak integrals from the solvent are used as a universal internal standard to correct volume variations in NMR tubes, thereby improving the accuracy and precision of esqNMR method. This simple yet effective technique is described in this talk. Practical considerations for successful implementation are investigated. 2H SOLCOR can be applied anywhere esqNMR is used, including where precious samples need to be accurately quantified for qualification as an authentic analytical standard. The technique also lends itself to accurate quantitation in situations where sample treatment is necessary.
Our second speaker is Prof. Vito Gallo from the Technical University of Bari in Italy. He will present “Community-built calibration systems for the development of non-targeted NMR”.
You are welcome to register and attend for free. Registration & attendance is limited. The webinar will take place on July 29th, 2021 @ 10:00 (Washington, D.C.), 15:00 (London), 16:00 (Berlin).