As the quantitative NMR (qNMR) technique has grown in favor during recent years, the metrological foundations for accurate and robust practices are currently being established. The first of its kind from NIST, ultra-pure and extensively-characterized NIST PS1 Benzoic Acid Primary Standard for quantitative NMR serves as a definitive, apical reference (calibrant) that establishes direct linkage of the qNMR technique to the International System of Units (SI) base unit mole. A realization of SI explicitly for molecular amount, it has a critical role in promoting accuracy and international comparability across the greater chemical measurement community, supporting clinical diagnostics, food safety and labeling, drug development, and biomedical research. This standard was developed through a Cooperative Research and Development Agreement (CRADA) between the NIST Chemical Sciences Division and Sigma-Aldrich Production GmbH, and in collaboration with the National Research Council (NRC) of Canada. It is being provided by NIST at no cost through Material Transfer Agreements (MTA) to National Metrology Institutes, other government agencies, secondary chemical reference standard producers, chemical and biomanufacturing industries, accredited measurement service providers, and other institutions with directives for high-accuracy traceable qNMR. More information… (by Michael Nelson, NIST)
The topic will be presented at the Validation Workshop (March 8, 2018) at 13:30 – come and join!